Who's the Bad Guy?

Question: Would you ever consider running a game in which the Titans were not the main enemy?

Sure. We've talked about ways to do so before, but generally, it's entirely possible not to use the Titans as your main enemies. If they're still in Tartarus, the gods are fully capable of scheming, fighting and even warring among themselves, both cross-pantheon and among their own people.

This is assuming the Titans are locked up or otherwise neutralized, however - by definition, the gods pretty much have to put their all into fighting them if they're loose, because if they don't the World is going to blow up and the Overworld sieges are going to end in tragedy for everyone.

Of course, the big question is always why - why is it you want to run a game Titan-free? Do you have some kind of plot that you feel like can't possibly work with the Titans in play (rare, because believe me, gods do not stop politicking and screwing one another over just because they're also fighting the Titans)? Is your idea going to have enough staying power over the lifetime of your Scions, with enough new challenges and possibilities at every level? Are you sure you want to cut yourself off from the vast options of the Titans and Titanspawn available in the world, and what are you planning to replace them with as the antagonistic mainstays of the game?

But, if you have answers for all those questions, then sure, go for it. One of our games, the Eastern Promises chronicle, is currently running with the Titans still imprisoned in Tartarus and the pantheons fighting a complex political influence war among themselves, and so far it's going very well (though the Titans and their minions are not entirely absent). There's no reason not to try something like that out if you have a plan; have a blast!

Titans and Titanspawn are fabulous antagonists, but they don't have to be the only ones you use in games. The gods antagonize one another quite frequently and impressively.